Domracheva started her sports career with cross-country skiing in 1992 but switched to biathlon in 1999. She originally represented Russia at youth level but received an offer to switch to Belarus in 2004.[2] She joined Belarus’ national biathlon team in 2006 (made her junior team debut in 2005).Domracheva won sprint and pursuit at the 2005 IBU Youth and Junior World Championships in Kontiolahti (Finland). She finished 40th in the individual race (the diopter fell off, and she missed 5 targets at the third shooting stage.)Domracheva took 3rd place in the pursuit and 4th place in the individual events at the 2006 Junior World Championships in Presque Isle, Maine. In 2007 she picked up two silver medals in sprint and pursuit at the Junior World Championships in Martell, Italy.Her breakthrough came during the 2008/2009 season when she earned two third places and one second place.At the 2010 Winter Olympic Games in Vancouver, she won the bronze medal in the Women's 15-kilometer individual race at the Whistler Olympic Park venue. Later in the same season, on 13 March, she won her first World Cup race in the sprint in Kontiolahti, Finland. The next day she also won the pursuit.Domracheva was named Belarus' Female Athlete of the Year in 2010, and was also given the title of Honoured Master of Sport that year.In 2014 Domracheva was given the Hero of Belarus medal, after was a won three gold medals at the 2014 Winter Olympics.In August 2015, Domracheva was decided that will miss 2015–16 World Cup season due to mononucleosis which was diagnosed in July.She is coached by former World Champion and Olympic medallist Klaus Siebert.