He is my friend.
Отрицательный: Isn't he my friend?
Вопросительный: Is he my friend?
Специальный: Whose friend is he?
My brother likes ice-cream.
Отрицательный: Doesn't my brother like ice-cream?
Вопросительный: Does my brother like ice-cream?
Специальный: What does my brother like?