He is my friend.
Is he my friend?
He isn't my friend.
I have got many friend.
I haven't got many friend.
Have I got many friend?
She is a singer.
Is she a singer?
She isn't a singer.
They are brothers.
Are they brothers?
They aren't brothers.
He has got a kitten.
He hasn't got a kitten.
Has he got a kitten?
It is his bicycle.
Is it his bicycle?
It isn't his bicycle.