(1/4-2/3)*(4/5-2/15)*(-3/5)=

$( \frac{1}{4}- \frac{2}{3} )*( \frac{4}{5} - \frac{2}{15} )*(- \frac{3}{5} )= \frac{1}{6}$

1) $\frac{1}{4}- \frac{2}{3}= \frac{1*3}{4*3}- \frac{2*4}{3*4}= \frac{3}{12}- \frac{8}{12}=- \frac{5}{12}$
2) $\frac{4}{5}- \frac{2}{15}= \frac{4*3}{5*3}- \frac{2}{15} = \frac{12}{15}- \frac{2}{15}= \frac{10}{15}= \frac{2}{3}$
3) $- \frac{5}{12} * \frac{2}{3}*(- \frac{3}{5} )= \frac{5*2*3}{12*3*5}= \frac{1}{6}$