№2
1. isn't
2. am not
3. are
4. is
№3
1. Have we English on Friday?; We don't have English on Friday
2. Does she speak French very well?; She doesn't speak French very well
3. Is John a student?; John is not a student
№4
1. Does his wife go to the office in the morning?
2. Is it his wife go to the office in the morning?