......in Regent Street,если предлог on the street-то это американский вариант.
İt is in 22 Regent Street in a building......
There is a cinema near(behind, opposite )it......
.....our offices are in the Tourism house.
We are on the second floor.
R.restaurant is above us.İt's on the top of Tourism house,and we're just under it.
İt is right near the underground station.