The supermarket is next to the post office.
Общий: Is the supermarket next to the post office?
Разделительный: The supermarket is next to the post office, isn't it?
Альтернативный: Is the supermarket next to the post office or the barbershop?
Специальный: What is the supermarket next to?
Вопрос к подлежащему: What is next to the supermarket?